Expertises
Medicine and Dentistry
- Vascular Bundle
- Endothelial Cell
- Induced Pluripotent Stem Cell
- Macrophage
- Thrombosis
- Vascular Disease
Engineering
- Models
Biochemistry, Genetics and Molecular Biology
- Vascularization
Organisaties
Publicaties
2025
Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19 (2025)Lab on a chip, 25(7), 1787-1800. Weener, H. J., van Haaps, T. F., van Helden, R. W. J., Albers, H. J., Haverkate, R., Middelkamp, H. H. T., Ridderikhof, M. L., van Mens, T. E., van den Berg, A., Mummery, C. L., Orlova, V. V., Middeldorp, S., van Es, N. & van der Meer, A. D.https://doi.org/10.1039/d4lc00848k
2024
Data of manuscript Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19 (2024)[Dataset Types › Dataset]. 4TU.Centre for Research Data. Weener, H., van Haaps, T., van Helden, R., Albers, H., Haverkate, R., Middelkamp, H., Ridderikhof, M., van Mens, T., van den Berg, A. & Mummery, C.https://doi.org/10.4121/5bb846d8-ed30-4e2e-bfe3-4fb607cbe8edStandardizing designed and emergent quantitative features in microphysiological systems (2024)Nature Biomedical Engineering, 8, 941-962. Nahon, D., Moerkens, R., Aydogmus, H., Lendemeijer, B., Martínez-Silgado, A., Stein, J., Dostanić, M., Frimat, J.-P., Gontan, C., de Graaf, M. N. S., Hu, M., Kasi, D., Koch, L. S., Le, K., Lim, S., Middelkamp, H. H. T., Mooiweer, J., Montreux-Ragot, P., Niggl, E., … Mummery, C. L.https://doi.org/10.1038/s41551-024-01236-0Embedded macrophages induce intravascular coagulation in 3D blood vessel-on-chip (2024)Biomedical microdevices, 26(1). Article 2. Middelkamp, H. H. T., Weener, H. J., Gensheimer, T., Vermeul, K., Heus, L. E. d., Albers, H. J., Berg, A. v. d. & Meer, A. D. v. d.https://doi.org/10.1007/s10544-023-00684-wConsidering future qualification for regulatory science in the early development of microphysiological systems: a case study of microthrombosis in a Vessel-on-Chip (2024)Frontiers in Toxicology, 6. Article 1513002. Weener, H. J., Middelkamp, H. H. T. & Van der Meer, A. D.https://doi.org/10.3389/ftox.2024.1513002
2023
Tracking the dynamics of thrombus formation in a blood vessel-on-chip with visible-light optical coherence tomography (2023)Biomedical optics express, 14(11), 5642-5655. Cuartas Velez, C. A., Middelkamp, H. H. T., van den Berg, A., van der Meer, A. & Bosschaart, N.https://doi.org/10.1364/BOE.500434Microfluidic vessels-on-chips for vascular disease modelling (2023)[Thesis › PhD Thesis - Research UT, graduation UT]. University of Twente. Middelkamp, H. H. T.https://doi.org/10.3990/1.9789036557245The effect of embedded macrophages on intravascular coagulation in 3D vessels-on-chips (2023)In Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023. Middelkamp, H. H. T., Weener, H. J., Gensheimer, T., Vermeul, K., de Heus, L. E., Albers, H. J., van den Berg, A. & van der Meer, A.
2022
A Blood-vessel-on-chip to characterize trained immunity in endothelial cells (2022)[Contribution to conference › Poster] EUROoCS Annual Meeting 2022. Le, K., Goosen - Middelkamp, H. H. T., Do, L., Netea, M., Jonkers, I., Orlova, V., Withoff, S., van der Meer, A. & Kumar, V.
2021
Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases (2021)Cardiovascular Research, 117(14), 2742-2754. Paloschi, V., Sabater-Lleal, M., Middelkamp, H., Vivas, A., Johansson, S., van der Meer, A., Tenje, M. & Maegdefessel, L.https://doi.org/10.1093/cvr/cvab088
Onderzoeksprofielen
Adres
Universiteit Twente
Horst Complex (gebouwnr. 20), kamer ZH113
De Horst 2
7522 LW Enschede
Universiteit Twente
Horst Complex ZH113
Postbus 217
7500 AE Enschede
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