prof.dr. J. Prakash (Jai)

Hoogleraar - Engineered Therapeutics


Stellate Crystal
Medicine & Life Sciences
Cancer-Associated Fibroblasts
Hepatic Stellate Cells
Liver Cirrhosis
Pancreatic Stellate Cells


  • ScarTec Therapeutics
    ScarTec Therapeutics


Rimal, R., Desai, P., Daware, R., Hosseinnejad, A. , Prakash, J. , Lammers, T., & Singh, S. (2022). Cancer-associated fibroblasts: Origin, function, imaging, and therapeutic targeting. Advanced drug delivery reviews, 189, [114504]. https://doi.org/10.1016/j.addr.2022.114504
Day, N. B., Dalhuisen, R., Loomis, N. E., Adzema, S. G. , Prakash, J., & Shields IV, C. W. (2022). Tissue-adhesive hydrogel for multimodal drug release to immune cells in skin. Acta biomaterialia, 150, 211-220. https://doi.org/10.1016/j.actbio.2022.07.053
Calejo, I. , Heinrich, M. A., Zambito, G., Mezzanotte, L. , Prakash, J. , & Teixeira, L. M. (2022). Advancing Tumor Microenvironment Research by Combining Organs-on-Chips and Biosensors. In Microfluidics and Biosensors in Cancer Research: Applications in Cancer Modeling and Theranostics (pp. 171-203). (Advances in Experimental Medicine and Biology; Vol. 1379). Springer Gabler. https://doi.org/10.1007/978-3-031-04039-9_7
Prakash, J. (2021). Integrin binding peptide and use of the same. (Patent No. JP2021101719).
Heinrich, M. A. , Mostafa, A. M. R. H., Morton, J. P., Hawinkels, L. J. A. C. , & Prakash, J. (2021). Translating complexity and heterogeneity of pancreatic tumor: 3D in vitro to in vivo models. Advanced drug delivery reviews, 174, 265-293. https://doi.org/10.1016/j.addr.2021.04.018
Hassan, S. , Heinrich, M., Cecen, B. , Prakash, J., & Zhang, Y. S. (2020). Biomaterials for on-chip organ systems. In Biomaterials for Organ and Tissue Regeneration: New Technologies and Future Prospects (pp. 669-707). Elsevier. https://doi.org/10.1016/B978-0-08-102906-0.00019-2
Mostafa, A. M. R. H. , Bansal, R. , & Prakash, J. (2020). Targeting Fibroblasts in Fibrosis and Cancer. In J. Brenneman, & M. R. Iyer (Eds.), Anti-fibrotic Drug Discovery (pp. 307-339). (RSC Drug Discovery Series; Vol. 2020-January, No. 73). Royal Society of Chemistry. https://doi.org/10.1039/9781788015783-00307
Schnittert, J. , Bansal, R. , Mardhian, D. F., van Baarlen, J., Östman, A. , & Prakash, J. (2019). Integrin α11 in pancreatic stellate cells regulates tumor stroma interaction in pancreatic cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(5), 6609-6621. https://doi.org/10.1096/fj.201802336R
Heinrich, M. A., Liu, W., Jimenez, A., Yang, J., Akpek, A., Liu, X., Pi, Q., Mu, X., Hu, N., Schiffelers, R. M. , Prakash, J., Xie, J., & Zhang, Y. S. (2019). 3D Bioprinting: from Benches to Translational Applications. Small, 15(23), [1805510]. https://doi.org/10.1002/smll.201805510
Akcora, B. Ö., Dathathri, E. , Ortiz-Perez, A. , Gabriël, A. V. , Storm, G. , Prakash, J. , & Bansal, R. (2019). TG101348, a selective JAK2 antagonist, ameliorates hepatic fibrogenesis in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(8), 9466-9475. https://doi.org/10.1096/fj.201900215RR

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In de Pers

Volkskrant Newspaper (Sep 2019): Verzwakte muur om kankercellen biedt chemo een kans. https://www.volkskrant.nl/cs-bf0bd786

Tubantia Newspaper,   “UT sets new steps in the treatment of pancreatic cancer”, 10 Nov 2017. https://www.tubantia.nl/regio/ut-zet-flinke-stappen-in-behandeling-alvleesklierkanker~a2caecdc/

U-Today, Science and Technology magazine  “Novel treatment to kill cancer by targeting stroma” Oct, 2017. https://www.utoday.nl/science/64599/unique-treatment-from-twente-effectively-kills-cancer

“KNCV Golden Master award 2017” to Marcel Heinrich (PhD student under my supervision), for his master project in my group on "Lipids against Cancer". https://www.c2w.nl/verenigingen-8751/lipide-tegen-kanker/item19184

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