dr. K. Broersen (Kerensa)

Universitair hoofddocent
TNW-BET-AST
Horst Complex ZH111
k.broersen@utwente.nl
+31534893655
Visitekaartje

Publicaties

2023
The TNFR1 antagonist Atrosimab reduces neuronal loss, glial activation and memory deficits in an acute mouse model of neurodegeneration, Article 10622. Ortí-Casañ, N., Boerema, A. S., Köpke, K., Ebskamp, A., Keijser, J., Zhang, Y., Chen, T., Dolga, A. M., Broersen, K., Fischer, R., Pfizenmaier, K., Kontermann, R. E. & Eisel, U. L. M.https://doi.org/10.1038/s41598-023-36846-2Robust Tissue Fabrication for Long-Term Culture of iPSC-Derived Brain Organoids for Aging Research, Article e64586. Koch, L. S., Buentello, D. C. & Broersen, K.https://doi.org/10.3791/64586
2022
Alzheimer’s Disease: Treatment Strategies and Their Limitations, Article 13954. Passeri, E., Elkhoury, K., Morsink, M., Broersen, K., Linder, M., Tamayol, A., Malaplate, C., Yen, F. T. & Arab-Tehrany, E.https://doi.org/10.3390/ijms232213954Engineering a multiplexed Blood-Brain Barrier-on-a-chip. University of Twente. Zakharova, M.https://doi.org/10.3990/1.9789036554299Use of standard U-bottom and V-bottom well plates to generate neuroepithelial embryoid bodies, Article e0262062. Buentello, D. C., Koch, L. S., Trujillo-De Santiago, G., Alvarez, M. M. & Broersen, K.https://doi.org/10.1371/journal.pone.0262062Engineering Organoids for in vitro Modeling of Phenylketonuria, Article 787242. Borges, A. C., Broersen, K., Leandro, P. & Fernandes, T. G.https://doi.org/10.3389/fnmol.2021.787242
2021
Transwell-Integrated 2 µm Thick Transparent Polydimethylsiloxane Membranes with Controlled Pore Sizes and Distribution to Model the Blood-Brain Barrier, Article 2100138. Zakharova, M., Tibbe, M. P., Koch, L. S., Le-The, H., Leferink, A. M., van den Berg, A., van der Meer, A. D., Broersen, K. & Segerink, L. I.https://doi.org/10.1002/admt.202100138A review of oxidative stress products and related genes in early alzheimer's disease, 977-1001. Cioffi, F., Adam, R. H. I., Bansal, R. & Broersen, K.https://doi.org/10.3233/JAD-210497Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation, Article 109300. Marasco, D., Vicidomini, C., Krupa, P., Cioffi, F., Huy, P. D. Q., Li, M. S., Florio, D., Broersen, K., De Pandis, M. F. & Roviello, G. N.https://doi.org/10.1016/j.cbi.2020.109300Cross-seeding of alpha-synuclein aggregation by amyloid fibrils of food proteins, Article 100358. Vaneyck, J., Segers-Nolten, I., Broersen, K. & Claessens, M. M. A. E.https://doi.org/10.1016/J.JBC.2021.100358
2020
Multiplexed blood-brain barrier organ-on-chip, 3132-3143. Zakharova, M., Palma do Carmo, M. A., van der Helm, M. W., Le-The, H., de Graaf, M. N. S., Orlova, V., van den Berg, A., van der Meer, A. D., Broersen, K. & Segerink, L. I.https://doi.org/10.1039/d0lc00399aMilk processing affects structure, bioavailability and immunogenicity of β-lactoglobulin, Article 874. Broersen, K.https://doi.org/10.3390/foods9070874Detection of amyloid aggregation in living systemsIn Protein Homeostasis Diseases: Mechanisms and Novel Therapies (pp. 127-152). Elsevier. Broersen, K.https://doi.org/10.1016/B978-0-12-819132-3.00007-5
2019
Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer's Disease, 981-1017. Cioffi, F., Adam, R. H. I. & Broersen, K.https://doi.org/10.3233/JAD-190863Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V, 443-457. Claes, F., Rudyak, S., Laird, A. S., Louros, N., Beerten, J., Debulpaep, M., Michiels, E., van der Kant, R., Van Durme, J., De Baets, G., Houben, B., Ramakers, M., Yuan, K., Gwee, S. S. L., Hernandez, S., Broersen, K., Oliveberg, M., Moahamed, B., Kirstein, J., … Schymkowitz, J.https://doi.org/10.1093/protein/gzaa008Investigation into the molecular complexity of Alzheimer's disease: an amyloid-ß centered approach. University of Twente. Cioffi, F.https://doi.org/10.3990/1.9789036548410

Onderzoeksprofielen

Adres

Universiteit Twente

Horst Complex (gebouwnr. 20), kamer ZH111
De Horst 2
7522 LW Enschede

Navigeer naar locatie

Organisaties

Scan de QR-code of
Download vCard