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dr. K. Broersen (Kerensa)

Universitair hoofddocent

Nevenactiviteiten

  • NIZO
    Project leader at NIZO food research

Publicaties

Recent
Passeri, E., Elkhoury, K., Morsink, M. , Broersen, K., Linder, M., Tamayol, A., Malaplate, C., Yen, F. T., & Arab-Tehrany, E. (2022). Alzheimer’s Disease: Treatment Strategies and Their Limitations. International journal of molecular sciences, 23(22), [13954]. https://doi.org/10.3390/ijms232213954
Borges, A. C. , Broersen, K., Leandro, P., & Fernandes, T. G. (2022). Engineering Organoids for in vitro Modeling of Phenylketonuria. Frontiers in Molecular Neuroscience, 14, [787242]. https://doi.org/10.3389/fnmol.2021.787242
Zakharova, M. (2022). Engineering a multiplexed Blood-Brain Barrier-on-a-chip. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036554299
Marasco, D., Vicidomini, C., Krupa, P. , Cioffi, F., Huy, P. D. Q., Li, M. S., Florio, D. , Broersen, K., De Pandis, M. F., & Roviello, G. N. (2021). Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation. Chemico-Biological Interactions, 334, [109300]. https://doi.org/10.1016/j.cbi.2020.109300
Broersen, K. (2020). Detection of amyloid aggregation in living systems. In Protein Homeostasis Diseases: Mechanisms and Novel Therapies (pp. 127-152). Elsevier Australia. https://doi.org/10.1016/B978-0-12-819132-3.00007-5
Claes, F., Rudyak, S., Laird, A. S., Louros, N., Beerten, J., Debulpaep, M., Michiels, E., van der Kant, R., Van Durme, J., De Baets, G., Houben, B., Ramakers, M., Yuan, K., Gwee, S. S. L., Hernandez, S. , Broersen, K., Oliveberg, M., Moahamed, B., Kirstein, J., ... Schymkowitz, J. (2019). Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V. Protein engineering, design & selection : PEDS, 32(10), 443-457. https://doi.org/10.1093/protein/gzaa008
Zakharova, M. , van der Helm, M., do Carmo, M. P. , Le-The, H. , Tibbe, M. , van der Meer, A. , Broersen, K. , Eijkel, J. , & Segerink, L. (2019). Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 432-433). The Chemical and Biological Microsystems Society.
Zakharova, M. , van der Helm, M., Palma Do Carmo, M. , Le The, H. , Tibbe, M. , van der Meer, A. , Broersen, K. , Eijkel, J. , & Segerink, L. (2019). Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. Poster session presented at 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019, Basel, Switzerland.
Cioffi, F. (2019). Investigation into the molecular complexity of Alzheimer's disease: an amyloid-ß centered approach. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente. https://doi.org/10.3990/1.9789036548410
Vicidomini, C. , Cioffi, F. , Broersen, K., Roviello, V., Riccardi, C., Montesarchio, D., Capasso, D., Gaetano, S. D., Musumeci, D., & Roviello, G. N. (2019). Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound. Future Medicinal Chemistry, 11(4), 285-302. https://doi.org/10.4155/fmc-2018-0473
Gera, J., Szögi, T., Bozsó, Z., Fülöp, L., Barrera, E. E., Rodriguez, A. M., Méndez, L., Delpiccolo, C. M. L., Mata, E. G. , Cioffi, F. , Broersen, K., Paragi, G., & Enriz, R. D. (2018). Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer. Bioorganic Chemistry, 81, 211-221. https://doi.org/10.1016/j.bioorg.2018.08.018

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Bezoekadres

Universiteit Twente
Faculty of Science and Technology
Horst Complex (gebouwnr. 20), kamer ZH111
De Horst 2
7522LW  Enschede

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Postadres

Universiteit Twente
Faculty of Science and Technology
Horst Complex  ZH111
Postbus 217
7500 AE Enschede

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