Welkom...

dr. K. Broersen (Kerensa)

Universitair hoofddocent

Expertises

Agglomeration
Alzheimer Disease
Peptides
Peptides
Therapeutics
Molecular Dynamics Simulation
Amyloid
Beta-Strand Protein Conformation
Alpha-Synuclein
Alpha-Synuclein
Amyloid Beta-Peptides

Publicaties

Recent
Gera, J., Szögi, T., Bozsó, Z., Fülöp, L., Barrera, E. E., Rodriguez, A. M., ... Enriz, R. D. (2018). Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer. Bioorganic Chemistry, 81, 211-221. DOI: 10.1016/j.bioorg.2018.08.018
Broersen, K., Ruipérez, V., & Davletov, B. (2018). Structural and aggregation properties of Alpha-Synuclein linked to phospholipase A2 action. Protein and Peptide Letters, 25(4), 368-378. DOI: 10.2174/0929866525666180326120052
Teodorowicz, M., Perdijk, O., Verhoek, I., Govers, C., Savelkoul, H. F. J., Tang, Y., ... Broersen, K. (2017). Optimized triton X-114 assisted lipopolysaccharide (LPS) removal method reveals the immunomodulatory effect of food proteins. PLoS ONE, 12(3), [0173778]. DOI: 10.1371/journal.pone.0173778
Ruzafa, D., Hernandez-Gomez, Y. S., Bisello, G., Broersen, K., Morel, B., & Conejero-Lara, F. (2017). The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein. PLoS ONE, 12(5), [e0178576]. DOI: 10.1371/journal.pone.0178576
Hubin, E., Cioffi, F., Rozenski, J., Van Nuland, N. A. J., & Broersen, K. (2016). Characterization of insulin-degrading enzyme-mediated cleavage of Aβ in distinct aggregation states. Biochimica et biophysica acta. General subjects, 1860(6), 1281-1290. DOI: 10.1016/j.bbagen.2016.03.010
Hubin, E., Vanschoenwinkel, B., Broersen, K., de Deyn, P. P., Koedam, N., van Nuland, N., & Pauwels, K. (2016). Could ecosystem management provide a new framework for Alzheimer's disease?Alzheimer's & dementia, 12(1), 65-74. DOI: 10.1016/j.jalz.2015.07.491
Barrera Guisasola, E. E., Andujar, S., Hubin, E., Broersen, K., Kraan, Y. M., Mendez, L., ... Enriz, R. D. (2015). New mimetic peptides inhibitors of Aβ aggregation: Molecular guidance for rational drug design. European journal of medicinal chemistry, 95, 136-152. DOI: 10.1016/j.ejmech.2015.03.042
Hubin, E., Deroo, S., Schierle, G. K., Kaminski, C., Serpell, L., Subramaniam, V., ... Sarroukh, R. (2015). Two distinct ß-sheet structures in Italian-mutant amyloid-beta fibrils: a potential link to different clinical phenotypes. Cellular and Molecular Life Sciences, 72(24), 4899-4913. DOI: 10.1007/s00018-015-1983-2
Cioffi, F., Rodriguez, A. M., Masman, M. F., Enriz, R. D., & Broersen, K. (2015). The multifactorial character of Alzheimer's disease. -.
Hubin, E., van Nuland, N. A. J., Broersen, K., & Pauwels, K. (2014). Transient dynamics of Abeta contribute to toxicity in Alzheimer's disease. Cellular and Molecular Life Sciences, 71(18), 3507-3521. DOI: 10.1007/s00018-014-1634-z
Adrover, M., Marino, L., Sanchis, P., Pauwels, K., Kraan, Y. M., Lebrun, P., ... Donoso, J. (2014). Mechanistic insights in glycation-induced protein aggregation. Biomacromolecules, 15(9), 3449-3462. DOI: 10.1021/bm501077j
Sarroukh, R., Hubin, E., Serpell, L. C., van Nuland, N., Broersen, K., & Raussens, V. (2014). Alzheimer's disease and cerebral amyloid angiopathy, doppelgangers?. 86-. DOI: 10.1002/pro.2504
Hubin, E., Sarroukh, R., de Roo, S., Raussens, V., van Nuland, N., & Broersen, K. (2013). Antiparallel beta-sheet architecture of italian-mutant amyloid-beta fibrils. -.
Hubin, E., Sarroukh, R., de Roo, S., Raussens, V., van Nuland, N., & Broersen, K. (2013). Antiparallel beta-sheet architecture of italian-mutant amyloid-beta fibrils. -.

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Contactgegevens

Bezoekadres

Universiteit Twente
Faculteit Technische Natuurwetenschappen
Horst Complex (gebouwnr. 20), kamer ZH155
De Horst 2
7522LW  Enschede

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Postadres

Universiteit Twente
Faculteit Technische Natuurwetenschappen
Horst Complex  ZH155
Postbus 217
7500 AE Enschede

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