Verbonden aan
Nevenactiviteiten
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NIZO
Project leader at NIZO food research
Publicaties
Recent
Koch, L. S., Buentello, D. C.
, & Broersen, K. (2023).
Robust Tissue Fabrication for Long-Term Culture of iPSC-Derived Brain Organoids for Aging Research.
Journal of visualized experiments,
2023(195), Article e64586.
https://doi.org/10.3791/64586
Passeri, E., Elkhoury, K., Morsink, M.
, Broersen, K., Linder, M., Tamayol, A., Malaplate, C., Yen, F. T., & Arab-Tehrany, E. (2022).
Alzheimer’s Disease: Treatment Strategies and Their Limitations.
International journal of molecular sciences,
23(22), Article 13954.
https://doi.org/10.3390/ijms232213954
Buentello, D. C.
, Koch, L. S., Trujillo-De Santiago, G., Alvarez, M. M.
, & Broersen, K. (2022).
Use of standard U-bottom and V-bottom well plates to generate neuroepithelial embryoid bodies.
PLoS ONE,
17(5 May), Article e0262062.
https://doi.org/10.1371/journal.pone.0262062
Borges, A. C.
, Broersen, K., Leandro, P., & Fernandes, T. G. (2022).
Engineering Organoids for in vitro Modeling of Phenylketonuria.
Frontiers in Molecular Neuroscience,
14, Article 787242.
https://doi.org/10.3389/fnmol.2021.787242
Zakharova, M. (2022).
Engineering a multiplexed Blood-Brain Barrier-on-a-chip. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente.
https://doi.org/10.3990/1.9789036554299
Cioffi, F., Adam, R. H. I.
, Bansal, R.
, & Broersen, K. (2021).
A review of oxidative stress products and related genes in early alzheimer's disease.
Journal of Alzheimer's Disease,
83(3), 977-1001.
https://doi.org/10.3233/JAD-210497
Zakharova, M.
, Tibbe, M. P.
, Koch, L. S.
, Le-The, H.
, Leferink, A. M.
, van den Berg, A.
, van der Meer, A. D.
, Broersen, K.
, & Segerink, L. I. (2021).
Transwell-Integrated 2 µm Thick Transparent Polydimethylsiloxane Membranes with Controlled Pore Sizes and Distribution to Model the Blood-Brain Barrier.
Advanced Materials Technologies,
6(12), Article 2100138. Advance online publication.
https://doi.org/10.1002/admt.202100138
Vaneyck, J.
, Segers-Nolten, I.
, Broersen, K.
, & Claessens, M. M. A. E. (2021).
Cross-seeding of alpha-synuclein aggregation by amyloid fibrils of food proteins.
Journal of biological chemistry,
296, Article 100358.
https://doi.org/10.1016/J.JBC.2021.100358
Marasco, D., Vicidomini, C., Krupa, P.
, Cioffi, F., Huy, P. D. Q., Li, M. S., Florio, D.
, Broersen, K., De Pandis, M. F., & Roviello, G. N. (2021).
Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo[c]phenanthridine and berberine-based compounds on β-amyloid aggregation.
Chemico-Biological Interactions,
334, Article 109300. Advance online publication.
https://doi.org/10.1016/j.cbi.2020.109300
Broersen, K. (2020).
Detection of amyloid aggregation in living systems. In
Protein Homeostasis Diseases: Mechanisms and Novel Therapies (pp. 127-152). Elsevier.
https://doi.org/10.1016/B978-0-12-819132-3.00007-5
Broersen, K. (2020).
Milk processing affects structure, bioavailability and immunogenicity of β-lactoglobulin.
Foods,
9(7), Article 874.
https://doi.org/10.3390/foods9070874
Zakharova, M., Palma do Carmo, M. A.
, van der Helm, M. W.
, Le-The, H., de Graaf, M. N. S., Orlova, V.
, van den Berg, A.
, van der Meer, A. D.
, Broersen, K.
, & Segerink, L. I. (2020).
Multiplexed blood-brain barrier organ-on-chip.
Lab on a chip,
20(17), 3132-3143.
https://doi.org/10.1039/d0lc00399a
Claes, F., Rudyak, S., Laird, A. S., Louros, N., Beerten, J., Debulpaep, M., Michiels, E., van der Kant, R., Van Durme, J., De Baets, G., Houben, B., Ramakers, M., Yuan, K., Gwee, S. S. L., Hernandez, S.
, Broersen, K., Oliveberg, M., Moahamed, B., Kirstein, J., ... Schymkowitz, J. (2019).
Exposure of a cryptic Hsp70 binding site determines the cytotoxicity of the ALS-associated SOD1-mutant A4V.
Protein engineering, design & selection : PEDS,
32(10), 443-457.
https://doi.org/10.1093/protein/gzaa008
Zakharova, M.
, van der Helm, M., do Carmo, M. P.
, Le-The, H.
, Tibbe, M.
, van der Meer, A.
, Broersen, K.
, Eijkel, J.
, & Segerink, L. (2019).
Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. In
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 (pp. 432-433). The Chemical and Biological Microsystems Society.
Zakharova, M.
, van der Helm, M., Palma Do Carmo, M.
, Le The, H.
, Tibbe, M.
, van der Meer, A.
, Broersen, K.
, Eijkel, J.
, & Segerink, L. (2019).
Multiplexed organ-on-chip device for increased throughput analysis of the tissue barrier function. Poster session presented at 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019, Basel, Switzerland.
Cioffi, F., Adam, R. H. I.
, & Broersen, K. (2019).
Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer's Disease.
Journal of Alzheimer's Disease,
72(4), 981-1017.
https://doi.org/10.3233/JAD-190863
Cioffi, F. (2019).
Investigation into the molecular complexity of Alzheimer's disease: an amyloid-ß centered approach. [PhD Thesis - Research UT, graduation UT, University of Twente]. University of Twente.
https://doi.org/10.3990/1.9789036548410
Hubin, E., Verghese, P. B., van Nuland, N.
, & Broersen, K. (2019).
Apolipoprotein E associated with reconstituted high-density lipoprotein-like particles is protected from aggregation.
FEBS letters,
593(11), 1144-1153. Advance online publication.
https://doi.org/10.1002/1873-3468.13428
Vicidomini, C.
, Cioffi, F.
, Broersen, K., Roviello, V., Riccardi, C., Montesarchio, D., Capasso, D., Gaetano, S. D., Musumeci, D., & Roviello, G. N. (2019).
Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound.
Future Medicinal Chemistry,
11(4), 285-302.
https://doi.org/10.4155/fmc-2018-0473
Gera, J., Szögi, T., Bozsó, Z., Fülöp, L., Barrera, E. E., Rodriguez, A. M., Méndez, L., Delpiccolo, C. M. L., Mata, E. G.
, Cioffi, F.
, Broersen, K., Paragi, G., & Enriz, R. D. (2018).
Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer.
Bioorganic Chemistry,
81, 211-221.
https://doi.org/10.1016/j.bioorg.2018.08.018
Broersen, K., Ruipérez, V., & Davletov, B. (2018).
Structural and aggregation properties of Alpha-Synuclein linked to phospholipase A2 action.
Protein and Peptide Letters,
25(4), 368-378.
https://doi.org/10.2174/0929866525666180326120052
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Verbonden aan Opleidingen
Bachelor
Vakken Collegejaar 2023/2024
Vakken in het huidig collegejaar worden toegevoegd op het moment dat zij definitief zijn in het Osiris systeem. Daarom kan het zijn dat de lijst nog niet compleet is voor het gehele collegejaar.
Vakken Collegejaar 2022/2023
Contactgegevens
Bezoekadres
Universiteit Twente
Faculty of Science and Technology
Horst Complex
(gebouwnr. 20), kamer ZH111
De Horst 2
7522LW Enschede
Postadres
Universiteit Twente
Faculty of Science and Technology
Horst Complex
ZH111
Postbus 217
7500 AE Enschede