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Expertises

  • Biochemistry, Genetics and Molecular Biology

    • SOX9
    • Fluorescence Recovery after Photobleaching
    • Transcription Factor
    • RUNX2
  • Material Science

    • Osteoblast
    • Polyethylene Glycol
  • Chemistry

    • Oxide
    • Poly(ethylene)

Organisaties

Publicaties

2025

Enhancing organoid technology with carbon-based nanomaterial biosensors: Advancements, challenges, and future directions (2025)Advanced drug delivery reviews, 222. Article 115592. Rezaei, Z., Wang, N., Yang, Y., Govindaraj, K., Velasco, J. J., Martinez Blanco, A. D., Bae, N. H., Lee, H. Y. & Shin, S. R.https://doi.org/10.1016/j.addr.2025.115592Covalent On-Cell Conjugation of Biomaterials Through Oxidative Phenolic Coupling Regulates Stem Cell Fate via Intracellular Biophysical Programming (2025)Advanced functional materials, 35(17). Article 2418963. Johnbosco, C., Becker, M., Willemen, N., Meteling, M., Govindaraj, K., Kamperman, T. & Leijten, J.https://doi.org/10.1002/adfm.202418963High-Throughput Single-Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC) (2025)Advanced materials, 37(6). Article 2415981. Meteling, M., Johnbosco, C., Wolfel, A., Conceição, F., Govindaraj, K., Teixeira, L. M. & Leijten, J.https://doi.org/10.1002/adma.202415981High‐Throughput Single‐Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC) (Adv. Mater. 6/2025): Graphical Abstract (2025)Advanced materials, 37(6). Meteling, M., Johnbosco, C., Wolfel, A., Conceição, F., Govindaraj, K., Moreira Teixeira, L. & Leijten, J.https://doi.org/10.1002/adma.202570044

2024

Dissecting SOX9 dynamics reveals its differential regulation in osteoarthritis (2024)Journal of cellular physiology, 239(12). Article e31443. Govindaraj, K., Kannan, S., Coutinho de Almeida, R., Jansen Klomp, L., Karperien, M., Meulenbelt, I. & Post, J. N.https://doi.org/10.1002/jcp.31443443-Physiological intracellular molecular crowding renormalizes osteoarthritic chondrocytes towards a healthy phenotype (2024)Osteoarthritis and cartilage, 32(Suppl. 1), S311-S312. Govindaraj, K., Meteling, M., Post, J. & Leijten, J.https://doi.org/10.1016/j.joca.2024.02.456TF-FRAP reveals number of cells in a subpopulation in hMSCs determines its differentiation potential (2024)Osteoarthritis and cartilage, 32(Supplement 1), S471-S471. Govindaraj, K., Kannan, S., Karperien, M. & Post, J.https://doi.org/10.1016/j.joca.2024.02.701Osmolarity-Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology (2024)Advanced science, 11(11). Article 2306722. Govindaraj, K., Meteling, M., van Rooij, J., Becker, M., van Wijnen, A. J., van den Beucken, J. J. J. P., Ramos, Y. F. M., van Meurs, J., Post, J. N. & Leijten, J.https://doi.org/10.1002/advs.202306722

2023

Altered intracellular molecular crowding plays a key role in osteoarthritis pathology (2023)[Contribution to conference › Poster] 47th FEBS Congress 2023. Govindaraj, K., Meteling, M. A. W. & Leijten, J.Mapping RUNX2 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells (2023)[Working paper › Preprint]. bioRxiv. Govindaraj, K., Kannan, S., Karperien, M. & Post, J. N.https://doi.org/10.1101/2023.03.30.534618

Onderzoeksprofielen

Adres

Universiteit Twente

Horst Complex (gebouwnr. 20), kamer ZH147
De Horst 2
7522 LW Enschede

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