Expertises
Biochemistry, Genetics and Molecular Biology
- SOX9
- Fluorescence Recovery after Photobleaching
- Transcription Factor
- RUNX2
Material Science
- Osteoblast
- Polyethylene Glycol
Chemistry
- Oxide
- Poly(ethylene)
Organisaties
Publicaties
2025
High-Throughput Single-Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC) (2025)Advanced materials, 37(6). Article 2415981. Meteling, M., Johnbosco, C., Wolfel, A., Conceição, F., Govindaraj, K., Teixeira, L. M. & Leijten, J.https://doi.org/10.1002/adma.202415981
2024
Covalent On-Cell Conjugation of Biomaterials Through Oxidative Phenolic Coupling Regulates Stem Cell Fate via Intracellular Biophysical Programming (2024)Advanced functional materials. Article 2418963 (E-pub ahead of print/First online). Johnbosco, C., Becker, M., Willemen, N., Meteling, M., Govindaraj, K., Kamperman, T. & Leijten, J.https://doi.org/10.1002/adfm.202418963Dissecting SOX9 dynamics reveals its differential regulation in osteoarthritis (2024)Journal of cellular physiology, 239(12). Article e31443. Govindaraj, K., Kannan, S., Coutinho de Almeida, R., Jansen Klomp, L., Karperien, M., Meulenbelt, I. & Post, J. N.https://doi.org/10.1002/jcp.31443Osmolarity-Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology (2024)Advanced science, 11(11). Article 2306722. Govindaraj, K., Meteling, M., van Rooij, J., Becker, M., van Wijnen, A. J., van den Beucken, J. J. J. P., Ramos, Y. F. M., van Meurs, J., Post, J. N. & Leijten, J.https://doi.org/10.1002/advs.202306722
2023
Altered intracellular molecular crowding plays a key role in osteoarthritis pathology (2023)[Contribution to conference › Poster] 47th FEBS Congress 2023. Govindaraj, K., Meteling, M. A. W. & Leijten, J.Mapping RUNX2 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells (2023)[Working paper › Preprint]. bioRxiv. Govindaraj, K., Kannan, S., Karperien, M. & Post, J. N.https://doi.org/10.1101/2023.03.30.534618
2022
Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis (2022)Carbohydrate polymers, 281. Article 118923. Allawadhi, P., Singh, V., Govindaraj, K., Khurana, I., Sarode, L. P., Navik, U., Banothu, A. K., Weiskirchen, R., Bharani, K. K. & Khurana, A.https://doi.org/10.1016/j.carbpol.2021.118923Osmolarity-Induced altered intracellular molecular crowding drives osteoarthritis pathology (2022)Osteoarthritis and cartilage, 30(Suppl. 1), S24-S25. Govindaraj, K., Meteling, M., Becker, M., Post, J. & Leijten, J.https://doi.org/10.1016/j.joca.2022.02.021
2021
Mapping SOX9 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells (2021)[Working paper › Preprint]. bioRxiv. Govindaraj, K., Khurana, S., Karperien, M. & Post, J. N.https://doi.org/10.1101/2021.11.29.470107Using FRAP to quantify changes in transcription factor dynamics after cell stimulation: Cell culture, FRAP, data analysis, and visualization (2021)In Osteoporosis and Osteoarthritis (pp. 109-139) (Methods in Molecular Biology; Vol. 2221). Humana Press. Govindaraj, K. & Post, J. N.https://doi.org/10.1007/978-1-0716-0989-7_9
Onderzoeksprofielen
Adres
Universiteit Twente
Horst Complex (gebouwnr. 20), kamer ZH147
De Horst 2
7522 LW Enschede
Universiteit Twente
Horst Complex ZH147
Postbus 217
7500 AE Enschede
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