Expertises

  • Medicine and Dentistry

    • Patient
    • Cardiovascular System
    • Pump
    • Left Ventricular Assist Device
    • Hemodynamic
    • Ventricular Assist Device
    • Hybrid
    • Heart Output

Organisaties

Publicaties

2026

Computational physiological models for hemodynamic management in critical care: a systematic literature review focusing on model design, credibility and clinical readiness (2026)Computers in biology and medicine, 205. Article 111561 (E-pub ahead of print/First online). Mulder, M. P., Warnaar, R. S. P., Arendshorst-Ruuls, T. F., van Loon, L. M., Meuwese, C. L., Broomé, M., Oppersma, E., Donker, D. W. & Fresiello, L.https://doi.org/10.1016/j.compbiomed.2026.111561More ECMO Flow, Same PCWP: Just What the Model Tells Us (2026)Journal of the American College of Cardiology (Accepted/In press). Meuwese, C. L., Donker, D. W., Fresiello, L., van Mieghem, N. M. & Broomé, M.https://doi.org/10.1016/j.jacc.2025.09.1612Comparison of a mean arterial pressure alarm to the hypotension prediction index in preventing intraoperative hypotension in elective moderate- to high-risk non-cardiac surgical patients: A study protocol for a blinded, parallel, randomized controlled trial with a non-inferiority framework (2026)Trials, 27(1). Article 104 (E-pub ahead of print/First online). Mulder, M. P., Florax, A. A., Harmannij-Markusse, M., Fresiello, L., Donker, D. W. & Potters, J.-W.https://doi.org/10.1186/s13063-025-09389-2Physiological-model-based neural network for modeling the metabolic–heart rate relationship during physical activities (2026)Computer methods and programs in biomedicine, 277. Article 109240 (E-pub ahead of print/First online). Zhang, Y., Fresiello, L., Veltink, P. H., Donker, D. W. & Wang, Y.https://doi.org/10.1016/j.cmpb.2026.109240

2025

Pmb-nn: Physiology-Centred Hybrid AI for Personalized Hemodynamic Monitoring from Photoplethysmography (2025)[Working paper › Preprint]. ArXiv.org. Zhang, Y., Fresiello, L., Veltink, P. H., Donker, D. W. & Wang, Y.https://doi.org/10.48550/arXiv.2512.10745A Physiological-Model-Based Neural Network Framework for Blood Pressure Estimation from Photoplethysmography Signals (2025)In 2025 47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) (Proceedings Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC); Vol. 2025). IEEE. Zhang, Y., Fresiello, L., Veltink, P. H., Donker, D. W. & Wang, Y.https://doi.org/10.1109/EMBC58623.2025.11251595Modeling age and sex variations of arterial pressure and cardiac hemodynamics in a virtual population using a 01-1DĀ cardiovascular simulator (2025)American journal of physiology : Heart and circulatory physiology, 329(5), H1212-H1228. Wardhana, G., van Loon, L. M., Potters, J.-W., Fransen, A., Lafort, A., Kilic, Y., Donker, D. W. & Fresiello, L.https://doi.org/10.1152/ajpheart.00387.2025All models are wrong but some provide seemingly surprising mechanistic insights into the complexity of venoarterial extracorporeal membrane oxygenation (2025)Perfusion, 40(5), 1294-1296. Fresiello, L. & Donker, D. W.https://doi.org/10.1177/02676591241263908Physiological-Model-Based Neural Network for Heart Rate Estimation during Daily Physical Activities (2025)[Working paper › Preprint]. ArXiv.org. Zhang, Y., Fresiello, L., Veltink, P. H., Donker, D. W. & Wang, Y.https://doi.org/10.48550/arXiv.2506.10144Effects of chronic volume deprivation on the ventricle (2025)Interdisciplinary cardiovascular and thoracic surgery, 40(6). Article ivaf124. Cools, B., Rega, F., Van De Bruaene, A., Van Hecke, M., Fresiello, L., Devleeschauwer, S., Brown, S., Claus, P. & Gewillig, M.https://doi.org/10.1093/icvts/ivaf124

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