Welkom...

M. Frega PhD (Monica)

Universitair docent

Expertises

Medicine & Life Sciences
Electrodes
In Vitro Techniques
Induced Pluripotent Stem Cells
Kleefstra Syndrome
Neurons
Engineering & Materials Science
Electrodes
Neurons
Stem Cells

Publicaties

Recent
van Rhijn, J. R., Shi, Y., Bormann, M., Mossink, B. , Frega, M., Recaioglu, H., Hakobjan, M., Klein Gunnewiek, T., Schoenmaker, C., Palmer, E., Faivre, L., Kittel-Schneider, S., Schubert, D., Brunner, H., Franke, B., & Nadif Kasri, N. (2022). Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons. Neurobiology of disease, 163, [105587]. https://doi.org/10.1016/j.nbd.2021.105587
Linda, K., Lewerissa, E. I., Verboven, A. H. A., Gabriele, M. , Frega, M., Klein Gunnewiek, T. M., Devilee, L., Ulferts, E., Hommersom, M., Oudakker, A., Schoenmaker, C., van Bokhoven, H., Schubert, D., Testa, G., Koolen, D. A., de Vries, B. B. A., & Nadif Kasri, N. (2022). Imbalanced autophagy causes synaptic deficits in a human model for neurodevelopmental disorders. Autophagy, 18(2), 423-442. https://doi.org/10.1080/15548627.2021.1936777
Mossink, B., van Rhijn, J. R., Wang, S., Linda, K., Vitale, M. R., Zöller, J. E. M., van Hugte, E. J. H., Bak, J., Verboven, A. H. A., Selten, M., Negwer, M., Latour, B. L., van der Werf, I., Keller, J. M., Klein Gunnewiek, T. M., Schoenmaker, C., Oudakker, A., Anania, A., Jansen, S., ... Nadif Kasri, N. (2022). Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks. Molecular Psychiatry, 27, 1-18. https://doi.org/10.1038/s41380-021-01117-x
Muzzi, L., Di Lisa, D., Arnaldi, P., Aprile, D., Pastorino, L., Martinoia, S. , & Frega, M. (2021). Rapid generation of functional engineered 3D human neuronal assemblies: Network dynamics evaluated by micro-electrodes arrays. Journal of neural engineering, 18(6), [066030]. https://doi.org/10.1088/1741-2552/ac3e02
Mossink, B., Verboven, A. H. A., van Hugte, E. J. H., Klein Gunnewiek, T. M., Parodi, G., Linda, K., Schoenmaker, C., Kleefstra, T., Kozicz, T., van Bokhoven, H., Schubert, D., Nadif Kasri, N. , & Frega, M. (2021). Human neuronal networks on micro-electrode arrays are a highly robust tool to study disease-specific genotype-phenotype correlations in vitro. Stem cell reports, 16(9), 2182-2196. https://doi.org/10.1016/j.stemcr.2021.07.001
Muzzi, L., Falappa, M., Maccione, A., di Lisa, D. , Frega, M., & Martinoia, S. (2021). Human derived cortical excitatory neurospheroids showed spontaneous activity on micro electrodes array. In 2021 10th International IEEE/EMBS Conference on Neural Engineering, NER 2021 (pp. 123-127). [9441261] (International IEEE/EMBS Conference on Neural Engineering, NER; Vol. 2021). IEEE Computer Society Press. https://doi.org/10.1109/NER49283.2021.9441261
Klein Gunnewiek, T. M., Van Hugte, E. J. H. , Frega, M., Guardia, G. S., Foreman, K., Panneman, D., Mossink, B., Linda, K., Keller, J. M., Schubert, D., Cassiman, D., Rodenburg, R., Vidal Folch, N., Oglesbee, D., Perales-Clemente, E., Nelson, T. J., Morava, E., Nadif Kasri, N., & Kozicz, T. (2020). m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity. Cell reports, 31(3), [107538]. https://doi.org/10.1016/j.celrep.2020.107538
Frega, M., Selten, M., Mossink, B., Keller, J. M., Linda, K., Moerschen, R., Qu, J., Koerner, P., Jansen, S., Oudakker, A., Kleefstra, T., van Bokhoven, H., Zhou, H., Schubert, D., & Nadif Kasri, N. (2020). Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype. Cell reports, 30(1), 173-186.e6. https://doi.org/10.1016/j.celrep.2019.12.002

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Vakken Collegejaar  2021/2022

Vakken in het huidig collegejaar worden toegevoegd op het moment dat zij definitief zijn in het Osiris systeem. Daarom kan het zijn dat de lijst nog niet compleet is voor het gehele collegejaar.
 

Vakken Collegejaar  2020/2021

Contactgegevens

Bezoekadres

Universiteit Twente
Faculty of Science and Technology
Technohal (gebouwnr. 18), kamer 3383
Hallenweg 5
7522NH  Enschede

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Postadres

Universiteit Twente
Faculty of Science and Technology
Technohal  3383
Postbus 217
7500 AE Enschede