prof.dr. H.B.J. Karperien (Marcel) | Universiteit Twente

Engineering & Materials Science

# Cartilage
# Hydrogels
# Stem Cells

Medicine & Life Sciences

# Cartilage
# Chondrocytes
# Hydrogels
# Mesenchymal Stem Cells

Chemistry

# Hydrogel

Faculty of Science and Technology (TNW), Developmental BioEngineering (DBE)

Orthros Medical
CSO and manager of Orthros Medical
LipoCoat b.v.
scientific advisor of LipoCoat b.v.
Hy2Care b.v.
member of the supervisory board
Hy2Care b.v.
CSO of Hy2Care b.v.
Karperien Holding b.v.
Management of Personal Holding
Saxion Hogeschool
Guest lecturer at Saxion Hogeschool

Wang, R. , Huang, X. , Zoetebier, B. , Dijkstra, P. J. , & Karperien, M. (2023). Enzymatic co-crosslinking of star-shaped poly(ethylene glycol) tyramine and hyaluronic acid tyramine conjugates provides elastic biocompatible and biodegradable hydrogels. Bioactive Materials, 20, 53-63. https://doi.org/10.1016/j.bioactmat.2022.05.020

Zoetebier, B., Schmitz, T. C., Ito, K. , Karperien, M., Tryfonidou, M. A. , & Paez, J. I. (2022). Injectable Hydrogels for Articular Cartilage and Nucleus Pulposus Repair: Status Quo and Prospects. Tissue Engineering - Part A, 28(11-12), 478-499. https://doi.org/10.1089/ten.tea.2021.0226

Koerselman, M. (2022). Small antibodies with a big opportunity: The variable domain of the heavy chain only antibody and its potential as disease modifying osteoarthritic drug . University of Twente. https://doi.org/10.3990/1.9789036554404

Koerselman, M., Warmink, K., Korthagen, N. M., van Midwoud, P. M., Verrips, T., Weinans, H. , & Karperien, M. (2022). Intra-articular drug depots for controlled release of heavy chain only antibodies blocking joint inflammation. Osteoarthritis and cartilage, 29(suppl. 1), S12-S13. https://doi.org/10.1016/j.joca.2021.02.032

Hendriks, J. , Schasfoort, R. , Koerselman, M., Dannenberg, M., Cornet, A. D., Beishuizen, A. , van der Palen, J. , Krabbe, J., Mulder, A. H. L. , & Karperien, M. (2022). High Titers of Low Affinity Antibodies in COVID-19 Patients Are Associated With Disease Severity. Frontiers in Immunology, 13, [867716]. https://doi.org/10.3389/fimmu.2022.867716

Paggi, C. A. , Hendriks, J. , Karperien, M. , & Gac, S. L. (2022). Emulating the chondrocyte microenvironment using multi-directional mechanical stimulation in a cartilage-on-chip. Lab on a chip, 22(9), 1815-1828. https://doi.org/10.1039/D1LC01069G

Paggi, C. A. (2022). Developing a joint-on-chip platform: A multi-organ-on-chip model to mimic healthy and diseased conditions of the synovial joints. University of Twente. https://doi.org/10.3990/1.9789036553261

Paggi, C. A. , Moreira Teixeira, L. , le Gac, S. , & Karperien, M. (2022). Joint-on-chip platforms: entering a new era of in vitro models for arthritis. Nature reviews rheumatology, 18, 217-231. https://doi.org/10.1038/s41584-021-00736-6

Zhong, L. , Koerselman, M. , Karbaat, L. , Kamperman, T. , Leijten, J. , Zoetebier, B. , & Karperien, M. (2021). Injectable hydrogels functionalized with antibody fragments as intra-articular cytokine sinks neutralizing pro-catabolic cytokines. Osteoarthritis and cartilage, 29(Suppl. 1), S50-S50. https://doi.org/10.1016/j.joca.2021.02.073

Govindaraj, K. , Khurana, S. , Karperien, M. , & Post, J. N. (2021). Mapping SOX9 transcriptional dynamics during multi-lineage differentiation of human mesenchymal stem cells. bioRxiv. https://doi.org/10.1101/2021.11.29.470107

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+31534895585 (bij geen gehoor)

marcel.karperien@utwente.nl

www.utwente.nl/tnw/dbe

Bezoekadres

Universiteit Twente
Faculty of Science and Technology
Horst Complex (gebouwnr. 20), kamer ZH143
De Horst 2
7522LW Enschede

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Postadres

Universiteit Twente
Faculty of Science and Technology
Horst Complex ZH143
Postbus 217
7500 AE Enschede

Faculty of Science and Technology (TNW), Developmental BioEngineering (DBE)

Universiteit Twente Drienerlolaan 5
7522 NB Enschede

+31 (0)53 489 9111
info@utwente.nl
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