Technohal

N. Doorn (Nina)

Promovendus
TNW-BIS-CNPH
Technohal 3384
n.doorn-1@utwente.nl
+31534897068
Visitekaartje

Expertises

  • Neuroscience

    • Dravet Syndrome
    • Stem Cell
    • Multielectrode Array
    • Electrophysiology
    • Neuron
    • Brain

  • Biochemistry, Genetics and Molecular Biology

    • Human Induced Pluripotent Stem Cell

  • Medicine and Dentistry

    • Functional Connectivity

Organisaties

Publicaties

2025

From Neuron to Network to Neurology: Deciphering multiscale electrophysiological measurements through biophysical modeling (2025)[Thesis › PhD Thesis - Research UT, graduation UT] (Accepted/In press). Doorn, N.https://publication-online.com/p/nina-doorn/Automated inference of disease mechanisms in patient-hiPSC-derived neuronal networks (2025)Communications Biology, 8(1). Article 768. Doorn, N., van Putten, M. J. A. M. & Frega, M.https://doi.org/10.1038/s42003-025-08209-2

2024

Breaking the burst: Unveiling mechanisms behind fragmented network bursts in patient-derived neurons (2024)Stem cell reports, 19(11), 1583-1597. Doorn, N., Voogd, E. J. H. F., Levers, M. R., van Putten, M. J. A. M. & Frega, M.https://doi.org/10.1016/j.stemcr.2024.09.001CACNA1A haploinsufficiency leads to reduced synaptic function and increased intrinsic excitability (2024)Brain, 139(4). Hommersom, M., Doorn, N., Puvogel, S., Lewerissa, E. I., Mordelt, A., Ciptasari, U., Kampshoff, F., Dillen, L., van Beusekom, E., Oudakker, A., Kogo, N., Dolga, A. M., Frega, M., Schubert, D. & van Bokhoven, H.https://doi.org/10.1093/brain/awae330Unraveling Dravet Syndrome: Exploring the complex effects of sodium channel mutations on neuronal networks (2024)Science Progress, 107(1). Doorn, N.https://doi.org/10.1177/00368504231225076

2023

Degree of differentiation impacts neurobiological signature and resistance to hypoxia of SH-SY5Y cells (2023)Journal of neural engineering, 20(6), 1741-2552. Article 066038. Voogd, E. J. H. F., Doorn, N., Levers, M. R., Hofmeijer, J. & Frega, M.https://doi.org/10.1088/1741-2552/ad17f3An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome (2023)Stem cell reports, 18(8), 1686-1700. Doorn, N., Hugte, E. J. H. v., Ciptasari, U., Mordelt, A., Meijer, H. G. E., Schubert, D., Frega, M., Nadif Kasri, N. & Putten, M. J. A. M. v.https://doi.org/10.1016/j.stemcr.2023.06.003Modeling the role of the thalamus in resting-state functional connectivity: Nature or structure (2023)PLoS Computational Biology, 19(8), e1011007. Article e1011007. Cabrera-Álvarez, J., Doorn, N., Maestú, F. & Susi, G.https://doi.org/10.1371/journal.pcbi.1011007

2021

Inter-device reproducibility of transcutaneous bilirubin meters (2021)Pediatric Research, 89(4), 770-775. Dam-Vervloet, A. J., van Erk, M. D., Doorn, N., Lip, S. G. J., Timmermans, N. A., Vanwinsen, L., de Boer, F. A., van Straaten, H. L. M. & Bosschaart, N.https://doi.org/10.1038/s41390-020-01118-6

Onderzoeksprofielen

Scan de QR-code of
Download vCard